Drain-Guard is an anchoring device for percutaneous drainage catheters that are protruding from the patient’s skin at an angle approximately perpendicular to the patient’s skin surface. The device consists of a skin-side surface with a skin friendly adhesive combined with a specially designed foam block that safely anchors catheters from 1 to 16 French Gauge. In addition, catheters are prevented from being expelled by the body and the secure anchoring of the catheter also prevents catheter movements from enlarging the catheter exit site. This is why less leakage is experienced. The soft foam support block can prevent kinking of the catheter. A transparent hydrocolloid cover allows continuous monitoring of the puncture site and provides an efficient protection against contamination.